The Serbian, who is seeking his 18th grand slam title, will face Colombia's Daniel Elahi Galan in the next round.
The victory ended a tumultuous two-week period for Flamengo. Following the defeat in Quito, the Rio outfit reported 16 COVID-19 cases in their squad, leaving them with only three regular first-team players for their Brazilian Serie A visit to Palmeiras last Sunday, which ended in a 1-1 draw.
Koeman also discussed rumors over interest from other clubs in winger Ousmane Dembele, whose sale would raise funds for new arrivals.
"In fact, we're still waiting for legal guidelines to run the games," Dortmund's sports director Michael Zorc complained.
Bayern started highly motivated in the encounter and took command while Hoffenheim kept 11 men behind the ball in the opening stages.
However, the wheels came off on Sunday as they crashed to a 6-1 defeat away to Atletico Madrid, who tore Granada's usually solid defense apart time after time.
The difficult negotiations with David Alaba are creating an unpleasant atmosphere. Bayern is said to have made an offer below the defenders demands and is risking losing one of its cornerstones in 2021 for free.
The Portuguese club have confirmed the move, which will see Nicolas Otamendi move in the opposite direction.
Standing 1.93m tall, Yang was a consistent threat in the paint, improving Shandong's halftime lead to 27 points.
Betis' horrible night was completed eight minutes from time when Alissa Mandi was sent off for two yellow cards to leave his side to play out the final minutes with 10 men.
Luo's compatriots Zhao Xintong, Xiao Guodong and Zhou Yuelong all have progressed into the second stage earlier.