Guangzhou still ranks first in the group, and will take on Dalian Pro in the group's last round.
Meanwhile, Real Betis has started the season with two wins from two games and looks a lot tougher under former Real Madrid and Manchester City coach Manuel Pellegrini than under Joan Ferrer 'Rubi' last season.
Spain's 12-time French Open winner Nadal, who is bidding for a record-equaling 20th Grand Slam, will play world No. 83 Egor Gerasimov of Belarus in the first round.
Former Barcelona midfielder Paulinho made it 2-0 for the defending champions in the 25th minute when another naturalized player Fei Nanduo, known as Fernandinho in Brazil, saw his shot parried by Henan goalkeeper Wu Yan, and the ball rebounded to the feet of Paulinho, who tapped it in.
Wuhan once had a good chance to pull one back in the 43rd minute when midfielder Liu Yun sent an accurate cross in the penalty area, but forward Dong Xuesheng failed to touch the ball.
Both sides lost several chances to take a lead in the first half, when Hebei's forwards Buya Turay and Markao failed to score in succession in the eighth minute, and Tianjin's 21-year-old midfielder Liu Ruofan missed three times in a row.
Dominic Calvert-Lewis hit a hat-trick as Everton also made it two wins from two games with a 5-2 thrashing of newly promoted West Brom, who have now lost twice and conceded eight times on their return to the top-flight.
With the win, Esteghlal edged Al Shorta on goal difference to finish second behind Al Ahli, who were confirmed group winners before the match. Enditem
JERUSALEM, Sept. 24 (Xinhua) -- Israeli outfit Hapoel Beer Sheva reached the play-off round of the UEFA Europa League after beating Scotland's Motherwell 3-0 on Thursday evening.
BEIJING, Sept. 24 (Xinhua) -- Spanish midfielder Dani Quintana scored the winning goal in stoppage time of the second half, helping Chengdu Better City beat Suzhou Dongwu 2-1 in the 4th round of China's second-tier league on Thursday.
Brazil will meet Bolivia in Sao Paulo on October 9 and Peru in Lima four days later.